The use of computed radiography for the determination of the impurities in 68Ga-EDTA by paper chromatography.

An ionic generator1) has been developed for preparation of gallium-68-labeled radiopharmaceuticals. This generator can be easily applied to the preparation of 68Ga-EDTA but some trials are necessary to determine the proper doses of EDTA. The half life of 68Ga is about 68 min and in our experiments, as it was necessary to check the purity of many samples at one time, we employed simplified mini paper chromatography in combination with autoradiography using a computed radiography system 2).